Hyperbaric Oxygen Therapy (HBOT) for Osteoradionecrosis
What is Osteoradionecrosis (ORN)?
Osteoradionecrosis means part of the jaw bone (usually the lower jaw/mandible) does not heal and becomes exposed after radiation therapy for head & neck cancers. It can show up months or years after radiation. The bone gets weak, blood flow reduces, and wounds don’t close easily. ORN is treatable—early care gives better results.
Common signs & symptoms
- Exposed bone in the mouth that doesn’t heal
- Pain, swelling, or infection (bad taste/discharge)
- Loose teeth or non-healing tooth socket after extraction
- Difficulty opening the mouth (trismus) or chewing
Causes of Osteoradionecrosis
Radiation therapy, while effective in destroying cancer cells, also damages healthy tissues and blood vessels.
This reduces oxygen supply to the bone, impairing healing and regeneration.
Common Triggers of ORN Include:
- Radiation dose above 60 Gy
- Dental extractions after radiation
- Trauma or ill-fitting dentures
- Poor oral hygiene
- Smoking or alcohol consumption
- Recurrent infections in the oral cavity
Why does ORN happen?
Radiation reduces tiny blood vessels in the bone and nearby soft tissue. With less blood and oxygen, healing slows. Dental extractions or minor injuries in the irradiated area can then trigger non-healing wounds.
Why Early Treatment is Critical
Studies show that treatment within the first 2 weeks of onset yields the highest recovery rates.
Delays can lead to permanent hearing damage.Traditionally, oral steroids and intratympanic steroid injections are used, but in many cases, adding Hyperbaric Oxygen Therapy (HBOT) significantly improves results.
Radiation reduces tiny blood vessels in the bone and nearby soft tissue. With less blood and oxygen, healing slows. Dental extractions or minor injuries in the irradiated area can then trigger non-healing wounds.
HBOT – Advanced Treatment for Sudden Hearing Loss
HBOT – Advanced Support for Healing in ORN
What is Hyperbaric Oxygen Therapy?
HBOT is a medical treatment where you breathe 100% oxygen in a pressurised chamber. This increases the oxygen reaching damaged bone and soft tissues, supports new blood vessel growth, reduces swelling, and helps wounds close. HBOT is used alongside dental/ENT care, antibiotics, and surgery when needed.
International Guidelines
- Undersea & Hyperbaric Medical Society (UHMS) recognises delayed radiation injury (bone and soft tissue) as an indication for HBOT. ORN of the jaw is a classic example. Undersea & Hyperbaric Medical Society
- The European Committee for Hyperbaric Medicine (ECHM) recommends HBOT for treatment of mandibular ORN and for prevention around dental procedures in irradiated jaws. PMC
- Evidence note (simple & honest): Studies show HBOT can improve healing in many patients with ORN, especially when started early or used around dental surgery in irradiated bone. Some recent trials report mixed results when HBOT is added after certain surgeries; your doctor will personalise the plan.
How HBOT helps in ORN
- Improves oxygen delivery to damaged bone and gums
- Reduces inflammation & swelling
- Stimulates new blood vessels (angiogenesis) for long-term healing
- Supports surgery by improving tissue quality
- Helps infected, non-healing wounds close faster when combined with standard care
Treatment Protocol at KiMi Health Hub & HBOT Centre, Jaipur
At KiMi Health Hub, we use a world-class Mono-place HBOT Chamber with:
- 100% pure oxygen under controlled pressure (no masks/hoods; the chamber is filled with oxygen)
- Single-patient use → reduces any cross-infection risk
- Transparent, comfortable design → better for anxious or claustrophobic patients
- Precise oxygen dosing and expert monitoring
- Direct supervision by Dr. Shivangi Jain (HBOT Specialist) with integrated care from Dr. Ajay Jain (ENT & Allergy Specialist)
Typical HBOT plan (individualised):
- Pressure: ~2.0–2.5 ATA
- Session time: ~90 minutes
- Number of sessions: commonly 30–40 for established ORN (may be staged with surgery)
- Before dental extraction in irradiated jaw: often 20–30 sessions before and 10 sessions after (the well-known Marx 30/10 protocol, adjusted to your case).
- HBOT is combined with:
- Dental/ENT procedures (debridement, sequestrectomy, reconstruction if needed)
- Antibiotics & oral hygiene
- Sometimes medical regimens like pentoxifylline + vitamin E ± clodronate (PENTO/PENTOCLO) where appropriate (doctor-guided).
Success Stories
Many patients with painful, non-healing jaw wounds after radiation have healed with HBOT + dental/ENT care.
Example: A 58-year-old gentleman with a non-healing socket after tooth removal in a previously irradiated jaw completed 30 HBOT sessions, had limited bone debridement, then 10 more HBOT sessions. The wound closed, pain reduced, and he returned to a normal diet.
(Individual results vary; your plan will be personalised.)
Benefits of Choosing KiMi Health Hub for HBOT
- Specialised Head–Neck ENT & HBOT care (Dr. Ajay Jain & Dr. Shivangi Jain)
- Integrated approach: Dental/ENT evaluation + HBOT + infection control
- State-of-the-art mono-place chamber—comfortable and precise
- Evidence-guided protocols aligned with UHMS/ECHM recommendations
- Safe, painless sessions with no downtime for most patients
FAQs – HBOT for Sudden Hearing Loss
Q1: When should HBOT be considered for ORN?
A: As early as possible when there is non-healing exposed bone after radiation, or before dental extractions in irradiated jaws to reduce complications.
Q2: Is HBOT safe?
A: Yes, when done under medical supervision. Side effects are usually mild and temporary (ear pressure, fatigue; rarely temporary short-sightedness).
Q3: Will HBOT work without surgery?
A: HBOT often helps tissues recover and can reduce the extent of surgery. Many patients still need dental/ENT procedures; HBOT aims to improve healing and outcomes. Evidence is strongest when used as part of a combined plan.
Q4: How many sessions are needed?
A: Typically 30–40 sessions for established ORN (often staged around procedures). For tooth removal in irradiated bone, a pre-/post-extraction course is commonly advised. Your doctor will tailor the number.
Book Your Consultation Today
If you or someone you know has experienced sudden hearing loss, don’t wait.
KiMi Health Hub & HBOT Centre offers the most advanced, safe, and effective HBOT for hearing restoration in Jaipur.
📍 Address: KiMi Health Hub & Allergy & HBOT Centre, Plot No. 6, Satya Vihar, Opposite Jain ENT Hospital, Lalkhoti, Jaipur – 302015
🌐 Website: kimihealthhub.com
📞 Call/WhatsApp: 8000109227 / 01414385414
📧 Email: admin@kimihealthhub.com | kimihealthhub@gmail.com
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